SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06467d0a000b433362b386fc2b7d74ca387b92c9cdab029c5671c9febfde6a50' 
  AND token = 'BmUOZCfSAjURxJpYsQ/DfE3f6VJWVT70zambv4wLtUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}