SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e9c4d2e23311767f79e1828710d8f6f58a675a5b7213af3ce8ff4a6a21758e' 
  AND token = 'eDzDlYwDQ57DIQVPCcq1tjgAwcQnSHjLJ156dL1ME/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}