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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a6eb0dfccfa75d407e3eae9450d288f8de3efce3d216da253a81c3deec0fd2' 
  AND token = 'Me4t+0b4tJlplD+dnXxRwgn2L27C0yUp1A49lAXFjQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}