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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52b3a72839f072f19cb086a38f6ceb54fd205e9fbeba907155bf90ee1b18e01' 
  AND token = 'hH0Es1e5bCVsc+Q6+IQ/nMEML+E1Ih2PtsoxN30Jdac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}