SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e694e1cfa6e408a72c5ba34bf66ce3d5c0949c7a2401541b848e46e2a1053919' 
  AND token = '1aFX5qBi8iZKzHi8kVQNJHo0cxG6hRsVIjKQGpUtU2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}