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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3156af8d286ff2348f81fea8daf2776cf09fd33b9e228b77b7ff0fece04806ee' 
  AND token = 'WBqey0erDGg6q8SbJkXv8JttbiPTb6GKulQ/cJmXHjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}