SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b308c336d2e1975ff639aba217bee42547bc4af3f28dec7a7428a0f04a62e9f' 
  AND token = 'ZWBVgzTN3ExYT1A/pntTidWTqDPoNcZBBO25Cyupkqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}