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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2f1644d34565abf3e97e509082b35319ee900c0dd57dcd10488328455c7e5ed' 
  AND token = 'qXWuAPEBjRzyMm0EfFXMoxCH21KAKsK9YpbCBp4sfvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}