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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df67ea1d63691fc975652f6b0479f765b7d75616f354fb265f6f3de736f229e5' 
  AND token = 'oVBE/9iwe85jHH8sdspQo49UnOMQD7lM/PNkqHEyLxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}