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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d83a72f60a07e4bf53d647a48cd78c912bc7b26a720baee8cbf568bd80fe98' 
  AND token = 'SY+fkL/oa/d1CBXzmQE4De1ZSltcIMrTlqRl0LB+vUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}