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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e161319c650669a078980e24ab5a3d813a700ea4056d1646e86f4c227965f0d' 
  AND token = 'Hgj35r9ukQO518oh+sx/qPDjEuHC5XOUOpaCUwCnL+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}