SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859c66edb70be6ac22be7326a61e915d8577df29c5803e47369012b6e46927f9' 
  AND token = 'CL5Q21Ch991vkyi+XJmegRB9GtGGDYGT+wBgP7/01d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}