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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '307d63ad6cff0fffe0be81534477117b972d60d4eb65320b2346af3ab92066a1' 
  AND token = 'UEPuiAbVV+AQdYYv9z5qyD7bOIqzTN6XQR45XKG4RIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00106

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}