SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f1b8b25e30c79458ef87fb8ee169654c3d4cad2e275d76eee4251856442bc4' 
  AND token = 'RriH+UbnJuCqtRbEcJQ5unaJQO+tLveyJ4PvN1yxHxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}