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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a4852d1c73505d0e547b517e3446e376bcc43a0b7f692342acff33f1099d11' 
  AND token = 'siOAX9bowITT9uzdtg3NNThnhcOmVZfuHQx8SfkH8+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}