SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2771ef0ed0d8f225d2caac55ca7e8a81dc9b71e5b375b8056f11503ef2e65627' 
  AND token = 'kJQRNCdQkLxDqXBgFSHwEoBgjRW9P64ceFi97Qc7s0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}