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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cc67051362a880749380ff0e59136bc2441ae9b4b87c4ac48cee3cd4ad52ec' 
  AND token = 'wp0GgQ5R51urX9K2jAK2fnXmI/Lkq+4OCTvlheTRtvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}