SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06bf5046347e0b99494489d43c36cdb3667cca181fb99215a162e7b2d2272b19' 
  AND token = 'BlC6Mb1lq8MdOTwl3TBAb5W4UifSt41XW7j3wxG04tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}