SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf591b88ac1d6693499d8997d41041d1fe5f32c2b2fce22c1353b45af2a1003' 
  AND token = 'diZQTwQbSmIeoWShyaUgwLYqVudWM0rA47qEOIGJQew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}