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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b27d2b59ac2428cb2405ad299f7f187e23238bd6cd2d697c6e161d6c36ff38c' 
  AND token = '5S7ArPvDg+uEu1CGmKeAE7Zut1EeQWk2lP4uvC7Smpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}