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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006ec5b06bff5737256441ac8071fed531aa270801d1dd007950b8deb3712bde' 
  AND token = '00Mw1xc3wCgHyhBK8T63+XXtyGt8MVE9Ey8CfQya4rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}