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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa5a98287cff3b257380a1bb41da298d7c28a8d0cb4c017cf7d2aaabe9f48c1' 
  AND token = 'Uv1uoyLLHdR+Xf+af7wozmnF2ErmRtZqkFmZ/h3dsvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}