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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae18fd8affb60b8899011d8d895b31072abee8cf9c0b31e6d615a4720d97ce4' 
  AND token = 'A3GtvSO40TnpE1Zu6DOpj7LYIYJ+3dJhK3dY9HI7BQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}