SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd403e4d3bb838eb8ac48e3fa38175134dac9ff9666b3e4f85286f75ca368c2b1' 
  AND token = 'JDPKfPJstKeVRgOpB71T+70l1GQUz1ODmOWVrjeu754=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}