SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de092591d0b265cbaae39c9f324c877f77f783a2f06a89638885f2616300dce' 
  AND token = 'Yxg4XNEPaPJXVegE6dUN+LH3cs4eQed7GUO3ceOxqXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}