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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6a22b09fd761ffa2975a2a36abe43e1f4659d1b539bfc0e9ae93e2082212f1' 
  AND token = 'skXfGVd4PV3b9vHAkkEbUhuBMT/xELxqw2M8ua0j2Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}