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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe324feb26885c9d0889aa36b442e40728d83f095d0ba1c8313890a3b9bd24e0' 
  AND token = 'e4QHAoBU45Uc9Vq27CTM4UdK1ui+j6X/NAG85l3USj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}