SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c40ecfc00916b95e6a8a369357811fbe8ce876a723acec1e3197c0bad64ce2' 
  AND token = 'B09/txS77Nt/q9Ky0YTr2mqIVc2Rc4+FFlxXhP/iMXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}