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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45907e63e388504f0d925f5cbaaeca580ad197f3a6007d2ad93ef344b71ef39b' 
  AND token = 'RfCxoFNyU+nbhz600E0cNSfsSOxNgkddlMG9r8rUehg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}