SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5274c8e359829c0c74f8ab19e5c8842bc51f31fa5c569132cf89326f48993db1' 
  AND token = 'OXxOPx9Uljk50gU8AFtL20bEr9rN6x7IvbtXIGDeoe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}