SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7308acd97ddb887f8c8ff0d3d6e2057cbce1a8ac166a6b2d8811c01982f8193' 
  AND token = 'mU4+Lc1SzZiOMMxhCTrFWZDRZcfKBwJO4vDuwJIOpLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}