SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12444bf5e1a5f46b82a3a8b882cacf434d456e824d2ba23a4f248b7bb9883ecb' 
  AND token = 'pw0Q/NvgQP1wvAbEUXnwbjC95+IUt11cRoe77fOF2Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}