SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145669da060f10135a35479e7091d43308610181f74d56d2c9443b1cc37e1a34' 
  AND token = 'tKEuu0pL2xWciNr54T4GoyyEWD8l5RcTEB99qOIStfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}