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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225c0d50c3043688cf6133d8aaf874972568e203cb6043dc8abc9bda9c4ffb79' 
  AND token = 'w+6jy2GaodmoJ0gkIV6Ldn94OK6ApcXuplbuU5ELfAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}