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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eea494b021be75d4a420a63d713e608bf77b634210682f69c51eb6d078b0d06' 
  AND token = '0StzcriLf//By73fIvZgaKAH2vJQyyJnC0DfIl3127s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}