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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452a63879ee97e6cee65274e1e07cba44fa04e09c825b818e647207ed84cad4c' 
  AND token = 'QdDB9wDVuAy8ob8cBsLhTbnl9Q3ihEVqZhoo2DRoOv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}