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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e08eb278613e7c55e3dd1d243accc9f385a7d557a718a63d4dd6d8a17acdb6a' 
  AND token = 'zMkKwOshYGrAymp4eGMRauWjy1z+sxjIiW/5EPHEeLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}