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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48f7e9e443db421710d3931608b8f25b7fd55699f8fe402a8a638f33d897feb' 
  AND token = 'aS0/sOH3JBNFlHuoQM88v73l4IbiEbuEKkSRzuhOPn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}