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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd502b5a52d8f84e81ca46b9cc1c3e70aedc8461494d999e40971d725e3f31aa9' 
  AND token = 'vUBCRy/t5P/mGKloH1cxkhIEkh7B3H5cEYT11Te5ZEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}