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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb33ee8cae5f064e3d223aa9e01a1c2bfefd25cb2edb3784f85a22bd5e59ca2' 
  AND token = 'T6xmxz4ZHIVJu6o4L+witRdR1zXp7cVKIQuNUaU7OFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}