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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b2c5e266b5557de68b5d4796741d185077331592d24fd435b017602f21f581' 
  AND token = 'WQFyzTaiBy1+D6UBufjAzcfL+LcUTxZc8mJq5XnqUG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}