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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43d295d729a1a2d5044a3ff358dfd3d58bd8c75b0ce201ad842966b9fb9a413' 
  AND token = 'd2b06bFB/Gu7fvW1R9KcbgIVQaMgYKG1cZPZlShhe68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}