SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd35f237679f6ae3c590664b37061e4185d91a781075f1d160623b74aadfe038' 
  AND token = 'HScY/HdHuGwTvM3HELbY/E8TdE4q89X7aZ7UlqYhJfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}