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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c7b54b643ed1255919e445a4f3ad57a2aecb91f5f228bfe720a203ef173106' 
  AND token = '8IbKtLltQ4b1x/NAOW6dP1TXFzZaUbx3QnSB3jJASys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}