SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac46da2675c6a14d36c9be856066a2ecda658e6d1708706885b39e308d553c8f' 
  AND token = 'Obugk6xcpbcZ1NEqNgTEKEl43eOFRYvTr4VlcKifOxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}