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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb290a9e3c4c07e2d8182b4d4134882f3d6f92b7b8f77f5a08113b8e75000bc6' 
  AND token = 'a+wJTp+RWIV4WTSIqIZeW21WiSqlfeToSEIVj5t28eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}