SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a32ed82b4a618a48e4d65419d7979d7f46e02124d9b6a4616b96f482403301' 
  AND token = '4a3Pu2KZhAjjE0fwOW/WCt2Lcull/rGUPrg2MNHqY80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}