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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c48410b9fcd135a41057591186e78972a88b3fb1271389cc1589a5c4de3942b' 
  AND token = 'n3hedj8ITspt5yhrC1RkrZGC6QGF100v9CjrXh8bCHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}