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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b27409bc60c5d45f6dd9bf9c74936a46655c6c8480dc890e54956eb1b6487042' 
  AND token = 'UzIBKIbJ9rTmY04h9Glc80dPPi0CY1BCW9Fcchv/gE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}