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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d457233c1d41fbbab8038c866321cf4be6e7a3e8b531b75c0d430c28d2848f3' 
  AND token = '06sVQbt7d6ZvWz2qSaiElHFBRyVDDvTWPVnDGeHJf5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}